A New Method of Constructing a Weighted PPI Network
نویسندگان
چکیده
منابع مشابه
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A Combination Method of Centrality Measures and Biological Properties to Improve Detection of Protein Complexes in Weighted PPI Networks
Introduction: In protein-protein interaction networks (PPINs), a complex is a group of proteins that allows a biological process to take place. The correct identification of complexes can help better understanding of the function of cells used for therapeutic purposes, such as drug discoveries. One of the common methods for identifying complexes in the PPINs is clustering, but this study aimed ...
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Proteins in the same protein complexes should highly interact with each other but rarely interact with the other proteins in protein-protein interaction (PPI) networks. All interaction network weighting schemes have been proposed so far in the literature in order to eliminate the noise inherent in interactome data. Visualization representation of data visually and is an important task in scient...
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متن کاملA Combination Method of Centrality Measures and Biological Properties to Improve Detection of Protein Complexes in Weighted PPI Networks
Introduction: In protein-protein interaction networks (PPINs), a complex is a group of proteins that allows a biological process to take place. The correct identification of complexes can help better understanding of the function of cells used for therapeutic purposes, such as drug discoveries. One of the common methods for identifying complexes in the PPINs is clustering, but this study aimed ...
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ژورنال
عنوان ژورنال: DEStech Transactions on Computer Science and Engineering
سال: 2017
ISSN: 2475-8841
DOI: 10.12783/dtcse/aita2017/16003